A recent simulation has provided an in-depth examination of female ejaculation, illustrating the role of Skene’s glands and what researchers believe is present in the expelled fluid.
A new simulation is shedding light on one of the more enigmatic aspects of female anatomy: the process that occurs during female ejaculation and the origins of the fluid involved.
Rather than treating it as an enigma or mere speculation, the explanation centers on the anatomy surrounding the urethra. Central to this are Skene’s glands, small glands located near the urethral opening in women, often referred to as the “female prostate.” This term arises from the relationship these glands have with the male prostate during early development.
Both Skene’s glands and the male prostate originate from the same type of embryonic tissue. While their functions may not be identical, this connection clarifies why scientists frequently draw parallels between them when examining fluid production, PSA levels, and sexual arousal.
To grasp the analogy, it’s beneficial to consider early embryonic development. In the initial stages, embryos possess tissue that can evolve into either testes or ovaries, influenced by genetic cues.
A Y chromosome typically directs this tissue toward forming testes, which subsequently generate hormones like testosterone. In the absence of that signal, the tissue matures into ovaries, leading to the typical development of female reproductive anatomy.
This common developmental pathway is a reason why Skene’s glands are often discussed in conjunction with the prostate. Although they are distinct organs, their shared origins help clarify why they may produce similar substances.

Skene’s glands are positioned on either side of the urethra, near the exit for urine. They are small, often compared to the size of a pea, and consist of clusters of cells that generate fluid, which then flows through tiny ducts into the urethra.
While their precise function is still under investigation, medical literature associates them with both urinary health and sexual well-being. They may play a role in lubricating the urethra, which could reduce the risk of irritation or infection.
The Cleveland Clinic describes Skene’s glands as small ducts adjacent to the urethra that assist with lubrication during sexual activity and may help guard against certain infections. During sexual arousal, enhanced blood flow can cause the surrounding tissues to swell, which may stimulate these glands to release mucus-like fluids that contribute to comfort and lubrication.
The primary source of confusion arises from the exit route of the fluid. Since female ejaculation occurs through the urethra, many people mistakenly assume the fluid is simply urine; however, researchers provide a more nuanced explanation.
A review indexed in PubMed on female ejaculation indicates that the fluid can differ from urine and may contain prostate-specific antigen (PSA). This distinction is a reason why discussions often reference Skene’s glands rather than solely focusing on the bladder.
This is also the reason female ejaculation and squirting are frequently mentioned together, although they are not always delineated as the same phenomenon. A separate medical explanation regarding female ejaculation and squirting highlights that anatomy, stimulation, and individual responses can all influence the experience.
Some women may expel fluid during orgasm, which is termed female ejaculation. The precise origin of the fluid continues to be a topic of medical inquiry, but it is believed that Skene’s glands contribute to at least some instances.
The volume of fluid released is generally modest, estimated at about “a teaspoon” or approximately 3 to 5 milliliters, and it exits the body through the urethra rather than the vagina.
The fluid has been likened to “diluted fat-free milk,” with an important characteristic being that it “does not have the odor of urine.” While primarily composed of water, it may also include electrolytes like sodium, potassium, and chloride.
Additionally, the fluid may contain prostate-specific antigen (often abbreviated as PSA), alongside glucose, fructose, immune proteins, and mucus. PSA is also present in male seminal fluid, which is why it is frequently mentioned in conversations about Skene’s glands.
However, this does not imply that Skene’s glands are merely a female counterpart to the prostate in every aspect. Experts make comparisons between the two due to their common origins and certain overlapping markers, but their functions are not completely identical.
The key takeaway is that female ejaculation encompasses more than just a singular fluid with a straightforward explanation. It exists at the intersection of anatomy, arousal, glandular secretions, and ongoing research regarding the functionality of Skene’s glands.
